C1ORF190 (LURAP1) (NM_001013615) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206634L4V

Lenti ORF particles, LURAP1 (mGFP-tagged) - Human chromosome 1 open reading frame 190 (C1orf190), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: C1ORF190
• Synonyms: C1orf190; LRAP35a; LRP35A
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001013615
• ORF Size: 717 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206634).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013615.1
• RefSeq Size: 1863 bp
• RefSeq ORF: 720 bp
• Locus ID: 541468
• UniProt ID: Q96LR2
• Cytogenetics: 1p34.1
• MW: 25.8 kDa
• Gene Summary: Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway (PubMed:21048106). In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity).[UniProtKB/Swiss-Prot Function]