Mouse Slc39a5 activation kit by CRISPRa

CAT#: GA209054

Slc39a5 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 39 (metal ion transporter), member 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Slc39a5
• Locus ID: 72002
• Kit Components:

  GA209054G1, Slc39a5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA209054G2, Slc39a5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA209054G3, Slc39a5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136237, NM_028051, NM_028092
• UniProt ID: Q9D856
• Synonyms: 1810013D05Rik; 2010205A06Rik; Zip5
• Summary: May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status.[UniProtKB/Swiss-Prot Function]