Human PSMD10 activation kit by CRISPRa

CAT#: GA103883

PSMD10 CRISPRa kit - CRISPR gene activation of human proteasome 26S subunit, non-ATPase 10

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PSMD10
• Locus ID: 5716
• Kit Components:

  GA103883G1, PSMD10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103883G2, PSMD10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103883G3, PSMD10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002814, NM_170750
• UniProt ID: O75832
• Synonyms: dJ889N15.2; p28; p28(GANK)
• Summary: This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011]