Sf3b4 (NM_001011951) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR206907L3V
- LentiORF®
Lenti ORF particles, Sf3b4 (Myc-DDK-tagged ORF) - Rat splicing factor 3b, subunit 4 (Sf3b4), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Rat Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Sf3b4 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001011951 |
ORF Size | 1272 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR206907).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001011951.1, NP_001011951.1 |
RefSeq Size | 1565 bp |
RefSeq ORF | 1275 bp |
Locus ID | 295270 |
UniProt ID | Q6AYL5 |
Cytogenetics | 2q34 |
Gene Summary | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.[UniProtKB/Swiss-Prot Function] |
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