GPCR TGR7 (MRGPRD) (NM_198923) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224023L1V

Lenti ORF particles, MRGPRD (Myc-DDK tagged) - Human MAS-related GPR, member D (MRGPRD), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GPCR TGR7
• Synonyms: MRGD; TGR7
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_198923
• ORF Size: 963 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224023).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_198923.2, NP_944605.2
• RefSeq Size: 966 bp
• RefSeq ORF: 966 bp
• Locus ID: 116512
• UniProt ID: Q8TDS7
• Cytogenetics: 11q13.3
• Protein Families: Druggable Genome, Transmembrane
• MW: 35.9 kDa
• Gene Summary: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).[UniProtKB/Swiss-Prot Function]