LEPRE1 (P3H1) (NM_022356) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222535L1V

Lenti ORF particles, P3H1 (Myc-DDK tagged) - Human leucine proline-enriched proteoglycan (leprecan) 1 (LEPRE1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LEPRE1
• Synonyms: GROS1; LEPRE1; OI8
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_022356
• ORF Size: 2208 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222535).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022356.2
• RefSeq Size: 2993 bp
• RefSeq ORF: 2211 bp
• Locus ID: 64175
• UniProt ID: Q32P28
• Cytogenetics: 1p34.2
• Domains: 2OG-FeII_Oxy, P4Hc
• Protein Families: Secreted Protein
• MW: 83.2 kDa
• Gene Summary: This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq, Aug 2011]