Ccp110 (NM_182995) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211433L3V

Lenti ORF particles, Ccp110 (Myc-DDK-tagged) - Mouse RIKEN cDNA 6330503K22 gene (6330503K22Rik), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Ccp110
• Synonyms: 6330503K22Rik; AA415922; AI427129; AW557948; CP110
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_182995
• ORF Size: 3015 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211433).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_182995.1
• RefSeq Size: 5024 bp
• RefSeq ORF: 3015 bp
• Locus ID: 101565
• UniProt ID: Q7TSH4
• Cytogenetics: 7 F2
• Gene Summary: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:23141541). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (PubMed:26965371). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (By similarity).[UniProtKB/Swiss-Prot Function]