Stam2 (NM_019667) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208368L4V

Lenti ORF particles, Stam2 (GFP-tagged) - Mouse signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Stam2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Stam2
• Synonyms: 1200004O12Rik; 5730456G07Rik; BB145015; Hbp
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_019667
• ORF Size: 1572 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208368).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019667.2, NP_062641.1
• RefSeq Size: 4124 bp
• RefSeq ORF: 1572 bp
• Locus ID: 56324
• UniProt ID: O88811
• Cytogenetics: 2 C1.1
• Gene Summary: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).[UniProtKB/Swiss-Prot Function]