Stam2 (NM_019667) Mouse Untagged Clone

CAT#: MC217395

Stam2 (untagged) - Mouse signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Stam2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Stam2
• Synonyms: 1200004O12Rik; 5730456G07Rik; BB145015; Hbp
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC217395 representing NM_019667
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCTCTGTTCACTGCCAACCCGTTCGAGCAAGATGTGGAAAAAGCCACAAATGAGTACAACACCACAG
  AAGACTGGAGTCTGATCATGGACATCTGTGACAGGGTTGGAAGCACTCCCAGTGGAGCAAAAGATTGCCT
  AAAAGCCATAATGAAAAGGGTAAACCATAAGGTCCCTCACGTTGCTCTGCAGGCATTGACCCTTCTTGGA
  GCTTGTGTGGCAAACTGTGGAAAGATATTTCATTTAGAAGTATGTTCCCGTGATTTTGCAACGGAAGTAC
  GTTCTGTGATAAAAAATAAGGCTCATCCTAAAGTATGTGAAAAACTAAAATCTCTAATGGTGGAATGGTC
  AGAAGAATTCCAGAAGGACCCCCAATTTAGTCTGATATCTGCAACTATTAAGTCTATGAAAGAAGAAGGG
  GTTACTTTTCCTTCCGCAGGCTCCCAGACTGTCGCGGCTGCTGCCAAAAACGGGACATCATTGAACAAAA
  ACAAAGAAGATGAGGACATAGCTAAAGCTATTGAGTTATCGTTGCAAGAGCAGAAGCAGCAGTACACGGA
  GACAAAGGCTTTGTACCCACCCGCAGAGAGTCAGCTCAATAACAAGGCTGCACGGAGAGTCAGAGCTTTA
  TACGACTTTGAAGCTGTTGAGGACAACGAGCTCACCTTTAAACATGGTGAGCTCATTACTGTTTTGGATG
  ACAGTGACGCCAACTGGTGGCAAGGAGAAAATCACAGAGGAACAGGACTCTTCCCCTCCAACTTTGTAAC
  GACTGACTTAAGCACAGAGGTTGAGACAGCAACGGTGGACAAATTGAATGTAATTGATGATGATGTGGAG
  GAAATTAAGAAATCAGAACCTGAGCCTGTTTATATAGATGAGGGTAAAATGGATAGAGCCCTGCAGATTC
  TCCAGAGCATAGATCCAAAAGAGTCAAAACCCGACTCCCAAGACCTCTTGGACTTGGAAGATGTTTGCCA
  ACAGATGGGTCCGATGATAGATGAAAAACTTGAAGAGATTGATAGGAAGCATTCAGAACTGTCTGAGTTG
  AACGTAAAGGTGCTGGAAGCCCTGGACCTGTACAATAAGTTGGTGAATGAAGCGCCTGTGTACTCGGTCT
  ATTCAAAGCTGCATCCCGCACATTACCCACCCGCAGCAGCTGGGGTTCCAGTGCAGACATATCCAGTCCA
  GTCGCATGGTGGAAACTACCTGGGCCACGGCATTCACCAAGTATCTGTTGCCCAGAACTATAACCTAGGA
  CCTGATCCTATGGGCTCGCTGAGATCTCTGCCTCCAAATATGAACTCGGTAACAGCACACACCGTCCAAC
  CTCCATACTTAAGCACTGGACAGGACACTGTCTCCAACCCTTCTTACATGAACCAGAGCTCTCGTCTTCA
  GGCAGCTGCTGGTACAGCTGCTTACACACAGCCTGTGGGGATGTCTACAGATGTGTCTTCTTTCCAGAAC
  ACAGCATCCGGTTTGCCTCAGCTGGCTGGCTTTCCAGTGGCAGTTCCTGCACCTGTCGCTGCACAGCCAC
  AAGCAAGCTACCACCAGCAGCCTCTCCTGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_019667
• Insert Size: 1572 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019667.2, NP_062641.1
• RefSeq Size: 4124 bp
• RefSeq ORF: 1572 bp
• Locus ID: 56324
• UniProt ID: O88811
• Cytogenetics: 2 C1.1
• Gene Summary: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).[UniProtKB/Swiss-Prot Function]