SLC39A7 (NM_001288777) Human Untagged Clone

CAT#: SC335490

SLC39A7 (untagged) - Human solute carrier family 39 (zinc transporter), member 7 (SLC39A7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC39A7
• Synonyms: D6S115E; D6S2244E; H2-KE4; HKE4; KE4; RING5; ZIP7
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC335490 representing NM_001288777.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACGACCTGCACGACGATCTGCAAGAGGACTTCCATGGCCACAGCCACAGTGCTGATCTCAGCAGCT
  CCATTTTTTGTCCTCTTCCTTATCCCCGTGGAGTCGAACTCTCCCCGGCATCGCTCTCTACTTCAGATC
  TTGCTCAGTTTTGCTTCCGGTGGGCTCCTGGGAGATGCTTTCCTGCACCTCATTCCTCATGCTCTTGAA
  CCTCATTCTCACCACACTCTGGAGCAACCCGGACATGGACACTCCCACAGTGGCCAGGGCCCCATTCTG
  TCTGTGGGACTGTGGGTTCTCAGTGGAATTGTTGCCTTTCTTGTCGTGGAGAAATTTGTGAGACATGTG
  AAAGGAGGACATGGTCACAGTCATGGACATGGACACGCTCACAGTCATACACGTGGAAGTCATGGACAT
  GGAAGACAAGAGCGTTCTACCAAGGAGAAGCAGAGCTCAGAGGAAGAAGAAAAGGAAACAAGAGGGGTT
  CAGAAGAGGCGAGGAGGGAGCACAGTACCCAAAGATGGGCCAGTGAGACCTCAGAACGCTGAAGAAGAA
  AAAAGAGGCTTAGACCTGCGTGTGTCGGGGTACCTGAATCTGGCTGCTGACTTGGCACACAACTTCACT
  GATGGTCTGGCCATTGGGGCTTCCTTTCGAGGGGGCCGGGGACTAGGGATCCTGACCACAATGACTGTC
  CTGCTACATGAAGTGCCCCACGAGGTCGGAGACTTTGCCATCTTGGTCCAGTCTGGCTGCAGCAAAAAG
  CAGGCGATGCGTCTGCAACTACTGACAGCAGTAGGGGCACTGGCAGGCACAGCCTGTGCCCTTCTCACT
  GAAGGAGGAGCAGTGGGCAGTGAAATTGCAGGTGGTGCAGGTCCTGGCTGGGTCCTGCCATTTACTGCA
  GGTGGCTTTATCTACGTAGCAACAGTGTCTGTGTTGCCCGAGCTGCTGAGGGAGGCATCACCATTGCAA
  TCACTTCTGGAGGTGCTGGGGCTGCTGGGGGGAGTTATCATGATGGTGCTGATTGCCCACCTTGAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001288777
• Insert Size: 1035 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001288777.1
• RefSeq Size: 1888 bp
• RefSeq ORF: 1035 bp
• Locus ID: 7922
• UniProt ID: Q92504
• Cytogenetics: 6p21.32
• Protein Families: Transmembrane
• MW: 36.3 kDa
• Gene Summary: The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which contains a shorter N-terminus, compared to isoform 1.