EDARADD (NM_080738) Human Untagged Clone
CAT#: SC120378
EDARADD (untagged)-Human EDAR-associated death domain (EDARADD), transcript variant B
"NM_080738" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | EDARADD |
Synonyms | ECTD11A; ECTD11B; ED3; EDA3 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC120378 sequence for NM_080738 edited (data generated by NextGen Sequencing)
ATGGCTTCACCGGACGACCCTCTGCGCGCAGATCATATGGTAAAGGAACCAGTGGAAGAC ACAGACCCTAGCACTTTATCCTTTAATATGTCAGACAAATATCCCATTCAAGATACGGAA CTCCCTAAAGCTGAAGAATGTGATACAATTACTTTGAACTGCCCACGAAATTCAGATATG AAAAATCAGGGAGAAGAAAATGGCTTTCCAGATAGCACTGGAGATCCTCTTCCAGAGATC AGCAAGGACAACTCCTGCAAAGAAAACTGTACTTGTTCCTCCTGCTTGCTCCGGGCCCCC ACCATAAGTGACTTGCTCAATGATCAGGACTTACTAGATGTGATCAGGATAAAGCTGGAT CCGTGTCACCCAACGGTGAAAAACTGGAGGAATTTTGCAAGCAAATGGGGGATGTCCTAT GACGAATTGTGCTTCCTGGAGCAGAGGCCACAGAGCCCCACCTTGGAGTTCTTGCTCCGG AACAGTCAGAGGACGGTGGGCCAGCTGATGGAGCTCTGCAGGCTCTACCACAGGGCCGAC GTGGAGAAGGTTCTGCGCAGGTGGGTGGACGAGGAGTGGCCCAAGCGGGAGCGTGGAGAC CCCTCCAGGCACTTCTAG Clone variation with respect to NM_080738.3 339 c=>t >OriGene 5' read for NM_080738 unedited
TAGGCGGCCGCGACATCGGCACGACCCGGGACACTCGGGGCCCCGCCTTGCGTCCCAGCC CCGGGTCGCGGCACCCCGGCTCCCGCCCCGCGCCTCTGGAGGGAGGTACCCGAGGGACCG CGCAGCGAAGGGGCTTTGCTAATTGCCAAAGCAGGAAGTGAGCTCGTGGAAGAAGCGAAG GAGGAGAAGAAGAAAGGAGGGGAAGGCGGAGGAGGGCAGGGGCGCGCAGAGCCACGGTTT GCTCCAGGCGCGTCGGAACCGCAGGACTTTTCATCCCCGTGGTCCCACGGTCCTCCCGCG CCCCGGAGGCCTGCCAGCCCCGCTCGGACGCTCGTTTGCCCCTAACCCGCCGCCATGGCT TCACCGGACGACCCTCTGCGCGCAGATCATATGGTAAAGGAACCAGTGGAAGACACAGAC CCTAGCACTTTATCCTTTAATATGTCAGACAAATATCCCATTCAAGATACGGAACTCCCT AAAGCTGAAGAATGTGATACAATTACTTTGAACTGCCCACGAAATTCAGATATGAAAAAT CAGGGAGAAGAAAATGGCTTTCCAGATAGCACTGGAGATCCTCTTCCAGAGATCANNGCA GGACACTCCTGNCAAGAAACTGTACTNTGTCCTCCTGCTTTGCTCNGGCCCCCACCATAA GTGACTTGCTCAATGATCANGACTTACTAGATGTGATCANGATAAAGCTGGATCCGTGTC ACCNCACGGTGAAAAACTGGNAGAATTTTTGCAGCAATGGGGGATGTCCTATGACGAATT GTGCTTCCTGNAGCAGAGGCACAGACCCCCACTTGGGAGTTCTTTGCTCGGACAATCANA GGACGGTGGCCCAGCTGATGGAGCTCTGCAGGCTCTACACAGG >OriGene 3' read for NM_080738 unedited
NNNNNGGGTACATCTAAGNAACCGCGGCCGCAATCTAGNGATCGATTTTTTTTTTTTTTT TTTTTCTGGGACGGACTCTCACTCTGTCTCCAGAACTGGTGTGCAGTGGCGCAATCTCGG CTCACTGCAACCTGCTTCTGTAGAAGTTCTAAGGAAGAGGTGCGAACTCCACGGCGGTGG GCAAGGGTAGCTAACTAGCAGCGGCCCCTACAAATGTTGCTCGGGGGTCTTGAGCTGCCG GAGTTGACACAAGGGGAGGGGTCTAATTAGCCACCAGGTGACTGAAGGGCTTGCCTGCCC ACAGCTTACTTGGCTGGGGGGTTTCTGAAGTTCCTGCCGGCAAACTTAGCCTTGCTGCCC AGCTCCTCTTCAATTCTGAGGAGCTGGTTGTACTTGGCCAAGCGCTCAGATCAGCAAGGG GCACCAGTCTTGAGCTGCCCAGGTCACAGCCCCACCACCAGGTCAGTGATGAAGGTATTT TCAGTCTCCCCAGAATGATGAGGCACCATGACACACCAACCATTGGCCTGGGCCAGCTTG CACGCCTGAAGGGACTCAGTCACAGAGCGAATCTGGTTCACTTTGAGCAGGAGGCAGTTG CACTTCTTCTCATTCACGGCCGAGGCTGTCCTCTTTGGGTTGGTCACTCTGAGATCATCC TCCACTACCTGGATTCCTGCACTGGCCGTGAACTTCTGCCAAGCTCCCCAGTCATCCTGG TCAAAGGGATCTTCAGTAGACACCACTGGGTAGTTTTTGATGAAGGACTTGTACAGGTCA GCCAGACCGTCAGGTGAGATGTACCTGGTGGGGGTCGTCGAGAAACTTGAATTCCCAGTC ATACTTTCCAGACCTGAAGAACTCGGAGGCCTCTACGTCCT |
Restriction Sites | NotI-NotI |
ACCN | NM_080738 |
Insert Size | 3500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_080738.2, NP_542776.1 |
RefSeq Size | 2891 bp |
RefSeq ORF | 618 bp |
Locus ID | 128178 |
UniProt ID | Q8WWZ3 |
Cytogenetics | 1q42.3-q43 |
Domains | enolase |
Protein Families | Druggable Genome |
Gene Summary | This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (B) differs in the 5' region compared to variant A. It encodes an isoform (B) that contains a distinct and shorter N-terminus, as compared to isoform (A). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219198 | EDARADD (Myc-DDK-tagged)-Human EDAR-associated death domain (EDARADD), transcript variant B |
USD 300.00 |
|
RC219198L1 | Lenti ORF clone of Human EDAR-associated death domain (EDARADD), transcript variant B, Myc-DDK-tagged |
USD 600.00 |
|
RC219198L2 | Lenti ORF clone of Human EDAR-associated death domain (EDARADD), transcript variant B, mGFP tagged |
USD 600.00 |
|
RC219198L3 | Lenti ORF clone of Human EDAR-associated death domain (EDARADD), transcript variant B, Myc-DDK-tagged |
USD 600.00 |
|
RC219198L4 | Lenti ORF clone of Human EDAR-associated death domain (EDARADD), transcript variant B, mGFP tagged |
USD 600.00 |
|
RG219198 | EDARADD (tGFP-tagged) - Human EDAR-associated death domain (EDARADD), transcript variant B |
USD 500.00 |
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