ELAC2 (NM_018127) Human Untagged Clone

CAT#: SC113690

ELAC2 (untagged)-Human elaC homolog 2 (E. coli) (ELAC2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ELAC2
• Synonyms: COXPD17; ELC2; HPC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113690 sequence for NM_018127 edited (data generated by NextGen Sequencing)
  ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGC
  ACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG
  CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG
  CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTC
  AACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA
  AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGC
  TTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGA
  CCTCCACAACTGGAAAAATACCTCGAAGCAATCAAAATATTTTCTGGTCCATTGAAAGGA
  ATAGAACTGGCTGTGCGGCCCCACTCTGCCCCAGAATACGAGGATGAAACCATGACAGTT
  TACCAGATCCCCATACACAGTGAACAGAGGAGGGGAAAGCACCAACCATGGCAGAGTCCA
  GAAAGGCCTCTCAGCAGGCTCAGTCCAGAGCGATCTTCAGACTCCGAGTCGAATGAAAAT
  GAGCCACACCTTCCACATGGTGTTAGCCAGAGAAGAGGGGTCAGGGACTCTTCCCTGGTC
  GTAGCTTTCATCTGTAAGCTTCACTTAAAGAGAGGAAACTTCTTGGTGCTCAAAGCAAAG
  GAGATGGGCCTCCCAGTTGGGACAGCTGCCATCGCTCCCATCATTGCTGCTGTCAAGGAC
  GGGAAAAGCATCACTCATGAAGGAAGAGAGATTTTGGCTGAAGAGCTGTGTACTCCTCCA
  GATCCTGGTGCTGCTTTTGTGGTGGTAGAATGTCCAGATGAAAGCTTCATTCAACCCATC
  TGTGAGAATGCCACCTTTCAGAGGTACCAAGGAAAGGCAGATGCCCCCGTGGCCTTGGTG
  GTTCACATGGCCCCAGCATCTGTGCTTGTGGACAGCAGGTACCAGCAGTGGATGGAGAGG
  TTTGGGCCTGACACCCAGCACTTGGTCCTGAATGAGAACTGTGCCTCAGTTCACAACCTT
  CGCAGCCACAAGATTCAAACCCAGCTCAACCTCATCCACCCGGACATCTTCCCCCTGCTC
  ACCAGTTTCCGCTGTAAGAAGGAGGGCCCCACCCTCAGTGTGCCCATGGTTCAGGGTGAA
  TGCCTCCTCAAGTACCAGCTCCGTCCCAGGAGGGAGTGGCAGAGGGATGCCATTATTACT
  TGCAATCCTGAGGAATTCATAGTTGAGGCGCTGCAGCTTCCCAACTTCCAGCAGAGCGTG
  CAGGAGTACAGGAGGAGTGCGCAGGACGGCCCAGCCCCAGCAGAGAAAAGAAGTCAGTAC
  CCAGAAATCATCTTCCTTGGAACAGGGTCTGCCATCCCGATGAAGATTCGAAATGTCAGT
  GCCACACTTGTCAACATAAGCCCCGACACGTCTCTGCTACTGGACTGTGGTGAGGGCACA
  TTTGGGCAGCTGTGCCGTCATTACGGAGACCAGGTGGACAGGGTCCTGGGCACCCTGGCT
  GCTGTGTTTGTGTCCCACCTGCACGCAGATCACCACACGGGCTTGCCAAGTATCTTGCTG
  CAGAGAGAACGCGCCTTGGCATCTTTGGGAAAGCCGCTTCACCCTTTGCTGGTGGTTGCC
  CCCAACCAGCTCAAAGCCTGGCTCCAGCAGTACCACAACCAGTGCCAGGAGGTCCTGCAC
  CACATCAGTATGATTCCTGCCAAATGCCTTCAGGAAGGGGCTGAGATCTCCAGTCCTGCA
  GTGGAAAGATTGATCAGTTCGCTGTTGCGAACATGTGATTTGGAAGAGTTTCAGACCTGT
  CTGGTGCGGCACTGCAAGCATGCGTTTGGCTGTGCGCTGGTGCACACCTCTGGCTGGAAA
  GTGGTCTATTCCGGGGACACCATGCCCTGCGAGGCTCTGGTCCGGATGGGGAAAGATGCC
  ACCCTCCTGATACATGAAGCCACCCTGGAAGATGGTTTGGAAGAGGAAGCAGTGGAAAAG
  ACACACAGCACAACGTCCCAAGCCATCAGCGTGGGGATGCGGATGAACGCGGAGTTCATT
  ATGCTGAACCACTTCAGCCAGCGCTATGCCAAGGTCCCCCTCTTCAGCCCCAACTTCAGC
  GAGAAAGTGGGAGTTGCCTTTGACCACATGAAGGTCTGCTTTGGAGACTTTCCAACAATG
  CCCAAGCTGATTCCCCCACTGAAAGCCCTGTTTGCTGGCGACATCGAGGAGATGGAGGAG
  CGCAGGGAGAAGCGGGAGCTGCGGCAGGTGCGGGCGGCCCTCCTGTCCAGGGAGCTGGCA
  GGCGGCCTGGAGGATGGGGAGCCTCAGCAGAAGCGGGCCCACACAGAGGAGCCACAGGCC
  AAGAAGGTCAGAGCCCAGTGA
  
  Clone variation with respect to NM_018127.6
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018127 unedited
  TTCAAATATTTGTATACGAACTCACTATAGGGCGGCCGCGATTCGGCACGAGGGTGGTGC
  ACGGNGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCA
  TGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCA
  CCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGC
  GCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGC
  AGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTCA
  ACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAA
  AGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCT
  TAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGAC
  CTCCACAACTGGAAAAATACCTCGAAGCAATCAAAATATTTTCTGGTCCATTGAAAGGAA
  TAGAACTGGCTGTGCGGCCCCACTCTGCCCCAGAATACGAGGATGAAACCATGACAGTTT
  ACCAGATCCCCATACACAGTGAACAGAGGAGGGGAAAGCACCAACCATGGCAGAGTCCAG
  AAAGGCCTCTCAGCAGGCTCAGTCCAGAGCGATCTTCAGACTCCGAGTCGAATGAAAATG
  AGCCACACCTTCCACATGGTGTTAGCCAGAGAAGAGGGGTCAGGNACTCTTTCCTGGTCG
  TAGCTTTCATCTGTAAGCTTCACTTAAAGAGAGGAACTTTCCTTGGTGCTCAAGCANAGG
  AGATGGCCTNCCAGTTGGACAGCTGCCTCGCTCCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018127 unedited
  GTAATGTAGGCTTGCCCTCCGAGGGCNCGAGAAAAAAAACTTTTTTTTTTNTCCAATTGC
  AATTTTTTTCTTTATTGCAGCTGAAATCTCTTTTCGTTAAGTCTCGGACACTTAAACCCA
  CTGATCCTGTTACTCTGCTTGCCTCCTGCTGCGCAGGGAATCATTTTGCTGGATTACAGG
  AAAGGTGCCGACGTCTGTTACCATGACTCCTTTAACCTCGGTTCTTGAAATGAAATTAGC
  TCATCTGCTTGCTTCCGTGTGGCAGCCTCCTGCCCCGACACTGCGCCAGGCACCAGCCCT
  AAGAGGCATCTATAGACTACCTGCCTTATGAGGGACCCCAAGCCTCGGCTCAGCTACATA
  CCACCTATACTGAGCTGACTCCTGGGGGACCGTGCTCTTCAACTCCTACCACCCAGGAGG
  ACACACCCGGTTGCGCGCGTGGGGCCCAACACCCACACGTTTCTGAGCACAGGGTCCACA
  CATCTTCACTGCACTCTGACCTTCTTGCACTGTGGCTTCTCTGCGTGGCCCCGCTTCTGT
  TGAGGCTCACCATCCTACCCCCCGACTGACACTCTCCTGCACAGGAGGTCCCACCGTACC
  TGTCGCACCTCCCCCTATTCCCTGCCCTACCTTATTCCCTTTTCGCCCCAACCACACGGC
  TTTCACTGCGGGAATCACCCTGCCCATTGCTGCAAAGCCTCCAAGCACACCTTATGCGGT
  CAAACGCAACTTTCCCTCTCTCGCTGCATTTGCCCCCGAAAGGGGCACCCTGACATATCG
  CCTGACTGACCGGCCTCCCCACTATGAACTCCGGGGTTCATCCTCATCCACACCCTGATG
  ACTGGGCACGATTANGCTTGGCGCCATTACCCTGCTTTTCTCTCATCACCACCCCTCACG
  GTGGCTTCCTGCTCAACCGACGCGGACCTTTTACCATTCGAACAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018127
• Insert Size: 3070 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_018127.4, NP_060597.3
• RefSeq Size: 2997 bp
• RefSeq ORF: 2481 bp
• Locus ID: 60528
• UniProt ID: Q9BQ52
• Cytogenetics: 17p12
• Domains: lactamase_B
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Gene Summary: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.