ELAC2 (NM_018127) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200764L2V

Lenti ORF particles, ELAC2 (mGFP-tagged) - Human elaC homolog 2 (E. coli) (ELAC2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: ELAC2
• Synonyms: COXPD17; ELC2; HPC2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_018127
• ORF Size: 2478 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200764).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018127.4, NP_060597.3
• RefSeq Size: 3814 bp
• RefSeq ORF: 2481 bp
• Locus ID: 60528
• UniProt ID: Q9BQ52
• Cytogenetics: 17p12
• Domains: lactamase_B
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 92.2 kDa
• Gene Summary: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]