Rtn4rl1 (NM_177708) Mouse Tagged Lenti ORF Clone
CAT#: MR207106L3
- LentiORF®
Lenti ORF clone of Rtn4rl1 (Myc-DDK-tagged) - Mouse reticulon 4 receptor-like 1 (Rtn4rl1)
"NM_177708" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Rtn4rl1 |
Synonyms | Ngr3; Ngrh2; Ngrl2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR207106).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_177708 |
ORF Size | 1338 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_177708.4 |
RefSeq Size | 3308 bp |
RefSeq ORF | 1338 bp |
Locus ID | 237847 |
UniProt ID | Q8K0S5 |
Cytogenetics | 11 B5 |
Gene Summary | Cell surface receptor that plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system (PubMed:22406547, PubMed:27339102). Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum (PubMed:27339102). Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (PubMed:26335717). Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans (PubMed:22406547). Binds heparin (PubMed:22406547). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC203049 | Rtn4rl1 (untagged) - Mouse reticulon 4 receptor-like 1 (Rtn4rl1), (10ug) |
USD 457.00 |
|
MG207106 | Rtn4rl1 (tGFP-tagged) - Mouse reticulon 4 receptor-like 1 (Rtn4rl1) |
USD 657.00 |
|
MR207106 | Rtn4rl1 (Myc-DDK-tagged) - Mouse reticulon 4 receptor-like 1 (Rtn4rl1) |
USD 457.00 |
|
MR207106L4 | Lenti ORF clone of Rtn4rl1 (mGFP-tagged) - Mouse reticulon 4 receptor-like 1 (Rtn4rl1) |
USD 757.00 |
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