Human SAMHD1 activation kit by CRISPRa

CAT#: GA108645

SAMHD1 CRISPRa kit - CRISPR gene activation of human SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SAMHD1
• Locus ID: 25939
• Kit Components:

  GA108645G1, SAMHD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108645G2, SAMHD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108645G3, SAMHD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015474, NM_001363729, NM_001363733
• UniProt ID: Q9Y3Z3
• Synonyms: CHBL2; DCIP; HDDC1; MOP-5; SBBI88
• Summary: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]