Human CCN1 (CYR61) activation kit by CRISPRa

CAT#: GA102360

CCN1 CRISPRa kit - CRISPR gene activation of human cellular communication network factor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CCN1
• Locus ID: 3491
• Kit Components:

  GA102360G1, CCN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102360G2, CCN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102360G3, CCN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001554
• UniProt ID: O00622
• Synonyms: CCN1; GIG1; IGFBP10
• Summary: The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]