PTPLA (HACD1) (NM_014241) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203054L2V

Lenti ORF particles, HACD1 (mGFP-tagged) - Human protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A (PTPLA), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PTPLA
• Synonyms: CAP; PTPLA
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_014241
• ORF Size: 864 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203054).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014241.2, NP_055056.2
• RefSeq Size: 1323 bp
• RefSeq ORF: 867 bp
• Locus ID: 9200
• UniProt ID: B0YJ81
• Cytogenetics: 10p12.33
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: Biosynthesis of unsaturated fatty acids
• MW: 32.4 kDa
• Gene Summary: The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]