Runx1t1 (NM_001111026) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR225849L4V

Lenti ORF particles, Runx1t1 (GFP-tagged) - Mouse runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Runx1t1
• Synonyms: Cbfa2t1h; ETO; MTG8
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001111026
• ORF Size: 1752 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR225849).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001111026.2, NP_001104496.1
• RefSeq Size: 5930 bp
• RefSeq ORF: 1755 bp
• Locus ID: 12395
• Cytogenetics: 4 5.88 cM
• Gene Summary: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity). Acts as a negative regulator of adipogenesis (PubMed:23527555).[UniProtKB/Swiss-Prot Function]