Ercc1 (NM_001127324) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224948L3V
- LentiORF®
Lenti ORF particles, Ercc1 (Myc-DDK-tagged) - Mouse excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Ercc1 |
Synonyms | Ercc-1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001127324 |
ORF Size | 735 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224948).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001127324.1, NP_001120796.1 |
RefSeq Size | 1241 bp |
RefSeq ORF | 738 bp |
Locus ID | 13870 |
UniProt ID | P07903 |
Cytogenetics | 7 9.6 cM |
Gene Summary | Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4 (By similarity).[UniProtKB/Swiss-Prot Function] |
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