ACE2 Human Recombinant Protein (Angiotensin Converting Enzyme 2)

CAT#: TP728051

Biotinylated Recombinant Human ACE-2(C-Avi-6His)

Specifications

Product Data

• Species: Human
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gln18-Ser740
• Tag: C-AVI&His
• Buffer: Supplied as a 0.2 um filtered solution of 20mMTris-HCl,300mMNaCl,1mMZnCl2,10%Glycerol,PH7.4 .
• Note: Biotinylated Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a AVI, 6His tag at the C-terminus.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 59272
• UniProt ID: Q9BYF1
• Summary: Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.