Mesothelin (MSLN) (NM_005823) Human Recombinant Protein
CAT#: TP723884
Purified recombinant protein of Human mesothelin (MSLN), transcript variant 1
USD 447.00
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Human Mesothelin, the region of Glu296-Gly580, from gene Accession# NM_005823
|
Tag | C-His |
Predicted MW | 32.9 kDa |
Concentration | lot specific |
Purity | >95%, as determined by Coomassie stained SDS-PAGE. |
Buffer | 1 x PBS, pH 7.2 |
Bioactivity | Human Mesothelin-Fc Chimera binds to immobilized recombinant human CA125/MUC16 in a dose-dependent manner. The ED50 for this effect is 4 – 20 ng/mL. |
Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
Storage | Store at -80°C. |
Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
Reference Data | |
RefSeq | NP_005814 |
Locus ID | 10232 |
UniProt ID | Q13421 |
Cytogenetics | 16p13.3 |
Refseq Size | 2197 |
Refseq ORF | 1863 |
Synonyms | MPF; SMRP |
Summary | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401768 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC415604 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 206.00 |
|
LC429380 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY401768 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 1 |
USD 436.00 |
|
LY415604 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 665.00 |
|
LY429380 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 436.00 |
|
PH302532 | MSLN MS Standard C13 and N15-labeled recombinant protein (NP_005814) |
USD 3,255.00 |
|
TP302532 | Recombinant protein of human mesothelin (MSLN), transcript variant 1, 20 µg |
USD 867.00 |
|
TP721264 | Human Mesothelin (R35-E298) Protein (C-His) |
USD 258.00 |
|
TP721265 | Human Mesothelin (E296-G580) Protein (C-His) |
USD 258.00 |
|
TP721266 | Human Mesothelin (E296-G580) Protein (C-His-Avi) |
USD 258.00 |
|
TP721267 | Biotinylated Human Mesothelin (E296-G580) Protein (C-His-Avi) |
USD 366.00 |
|
TP721268 | PE Conjugated Human Mesothelin (E296-G580) Protein (C-His) |
USD 366.00 |
|
TP721269 | APC Conjugated Human Mesothelin (E296-G580) Protein (C-His) |
USD 366.00 |
|
TP721270 | Human Mesothelin (E296-G580) Protein (C-Fc) |
USD 258.00 |
|
TP721271 | Human Mesothelin (E296-G580) Protein (C-Fc-Avi) |
USD 258.00 |
|
TP721272 | Biotinylated Human Mesothelin (E296-G580) Protein (C-Fc-Avi) |
USD 366.00 |
|
TP721273 | PE Conjugated Human Mesothelin (E296-G580) Protein (C-Fc) |
USD 366.00 |
|
TP721274 | APC Conjugated Human Mesothelin (E296-G580) Protein (C-Fc) |
USD 366.00 |
|
TP723954 | Human MSLN(296-580) Protein, mFc-His Tag |
USD 520.00 |
|
TP762350 | Purified recombinant protein of Human mesothelin (MSLN), transcript variant 2, Asn402-Thr581, with N-terminal His tag, expressed in E.coli, 50ug |
USD 249.00 |
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