IFNAR1 (NM_000629) Human Recombinant Protein
CAT#: TP720644
Purified recombinant protein of Human interferon (alpha, beta and omega) receptor 1 (IFNAR1)
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Lys28-Lys436
|
Tag | C-His |
Predicted MW | 48.18 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000620 |
Locus ID | 3454 |
UniProt ID | P17181 |
Cytogenetics | 21q22.11 |
Refseq Size | 6099 |
Refseq ORF | 1671 |
Synonyms | AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC |
Summary | The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway |
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Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400212 | IFNAR1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY400212 | Transient overexpression lysate of interferon (alpha, beta and omega) receptor 1 (IFNAR1) |
USD 436.00 |
|
TP762081 | Purified recombinant protein of Human interferon (alpha, beta and omega) receptor 1 (IFNAR1),Lys276-Asn416, with N-terminal His tag, expressed in E. coli, 50ug |
USD 261.00 |
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