I 309 (CCL1) (NM_002981) Human Recombinant Protein
CAT#: TP720604L
Purified recombinant protein of Human chemokine (C-C motif) ligand 1 (CCL1)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Lys24-Lys96
|
Tag | Tag Free |
Predicted MW | 8.62 kDa |
Concentration | lot specific |
Purity | Greater than 95% as determined by reducing SEC-HPLC and reducing SDS-PAGE. |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002972 |
Locus ID | 6346 |
UniProt ID | P22362 |
Cytogenetics | 17q12 |
Refseq Size | 594 |
Refseq ORF | 288 |
Synonyms | I-309; P500; SCYA1; SISe; TCA3 |
Summary | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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