PMP2 (NM_002677) Human Mass Spec Standard

CAT#: PH306053

PMP2 MS Standard C13 and N15-labeled recombinant protein (NP_002668)

Product Images

Coomassie blue staining of purified PMP2 protein (Cat# TP306053). The protein was produced from HEK293T cells transfected with PMP2 cDNA clone (Cat# RC206053) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC206053
• Predicted MW: 14.9 kDa
• Protein Sequence:
  Sequence Link

  >RC206053 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKNTEISFKLGQE
  FEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKMKGVVCTRIYEKV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_002668
• RefSeq Size: 3579
• RefSeq ORF: 396
• Synonyms: CMT1G; FABP8; M-FABP; MP2; P2
• Locus ID: 5375
• UniProt ID: P02689
• Cytogenetics: 8q21.13
• Summary: The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017]