Wdr45 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN319361LP
Wdr45 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Wdr45 |
Locus ID | 54636 |
Components |
KN319361G1, Wdr45 gRNA vector 1 in pCas-Guide CRISPR vector KN319361G2, Wdr45 gRNA vector 2 in pCas-Guide CRISPR vector KN319361LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001290792, NM_001290794, NM_001290795, NM_172372 |
UniProt ID | Q91VM3 |
Synonyms | C79260; DXImx38e; JM5; Sfc19; Wdrx1; WIPI-4 |
Summary | Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Activated by the STK11/AMPK signaling pathway upon starvation, WDR45 is involved in autophagosome assembly downstream of WIPI2, regulating the size of forming autophagosomes. Probably recruited to membranes through its PtdIns3P activity.[UniProtKB/Swiss-Prot Function] |
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Other Versions
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KN319361 | Wdr45 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN319361BN | Wdr45 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN319361RB | Wdr45 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN519361 | Wdr45 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA205747 | Wdr45 CRISPRa kit - CRISPR gene activation of mouse WD repeat domain 45 |
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