GAS1 Human Gene Knockout Kit (CRISPR)

CAT#: KN224804RB

GAS1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: GAS1
• Locus ID: 2619
• Components:

  KN224804G1, GAS1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN224804G2, GAS1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN224804RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_002048
• UniProt ID: P54826
• Synonyms: growth arrest-specific 1; Growth arrest-specific gene-1; OTTHUMP00000021599
• Summary: Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008]