TEP1 Human Gene Knockout Kit (CRISPR)

CAT#: KN223614LP

TEP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: TEP1
• Locus ID: 7011
• Components:

  KN223614G1, TEP1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN223614G2, TEP1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN223614LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001319035, NM_007110
• UniProt ID: Q99973
• Synonyms: p240; TLP1; TP1; TROVE1; VAULT2
• Summary: This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]