Nectin 3 (NECTIN3) Human Gene Knockout Kit (CRISPR)
CAT#: KN222962RB
PVRL3 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | Nectin 3 |
Locus ID | 25945 |
Components |
KN222962G1, Nectin 3 gRNA vector 1 in pCas-Guide CRISPR vector KN222962G2, Nectin 3 gRNA vector 2 in pCas-Guide CRISPR vector KN222962RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001243286, NM_001243288, NM_015480 |
UniProt ID | Q9NQS3 |
Synonyms | CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRR3 |
Summary | This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
Documents
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Other Versions
SKU | Description | Size | Price |
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KN222962 | NECTIN3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN222962BN | PVRL3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN222962LP | PVRL3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN422962 | PVRL3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA108650 | NECTIN3 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 3 |
USD 1,657.00 |
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