MYO18A Human Gene Knockout Kit (CRISPR)

CAT#: KN216905BN

MYO18A - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: MYO18A
• Locus ID: 399687
• Components:

  KN216905G1, MYO18A gRNA vector 1 in pCas-Guide CRISPR vector

  KN216905G2, MYO18A gRNA vector 2 in pCas-Guide CRISPR vector

  KN216905BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_078471, NM_203318, NM_001346765, NM_001346766, NM_001346767, NM_001346768
• UniProt ID: Q92614
• Synonyms: MYSPDZ; SPR210
• Summary: The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]