PNPLA3 Human Gene Knockout Kit (CRISPR)

CAT#: KN209577RB

PNPLA3 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: PNPLA3
• Locus ID: 80339
• Components:

  KN209577G1, PNPLA3 gRNA vector 1 in pCas-Guide CRISPR vector

  KN209577G2, PNPLA3 gRNA vector 2 in pCas-Guide CRISPR vector

  KN209577RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_025225
• UniProt ID: Q9NST1
• Synonyms: ADPN; C22orf20; iPLA(2)epsilon
• Summary: The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]