SLP76 (LCP2) Human Gene Knockout Kit (CRISPR)
CAT#: KN204404LP
LCP2 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
USD 450.00
USD 744.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | SLP76 |
Locus ID | 3937 |
Components |
KN204404G1, SLP76 gRNA vector 1 in pCas-Guide CRISPR vector KN204404G2, SLP76 gRNA vector 2 in pCas-Guide CRISPR vector KN204404LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_005565 |
UniProt ID | Q13094 |
Synonyms | SLP-76; SLP76 |
Summary | This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016] |
Documents
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Other Versions
SKU | Description | Size | Price |
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KN204404 | LCP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN204404BN | LCP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN204404RB | LCP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN404404 | LCP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA102670 | LCP2 CRISPRa kit - CRISPR gene activation of human lymphocyte cytosolic protein 2 |
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