CD147 (BSG) Human Gene Knockout Kit (CRISPR)

CAT#: KN203894LP

BSG - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: CD147
• Locus ID: 682
• Components:

  KN203894G1, CD147 gRNA vector 1 in pCas-Guide CRISPR vector

  KN203894G2, CD147 gRNA vector 2 in pCas-Guide CRISPR vector

  KN203894LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001322243, NM_001728, NM_198589, NM_198590, NM_198591
• UniProt ID: P35613
• Synonyms: 5F7; CD147; EMMPRIN; OK; TCSF
• Summary: The protein encoded by this gene, basigin, is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Basigin is also a member of the immunoglobulin superfamily, ubiquitously expressed in various tissues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]