NNMT Human Gene Knockout Kit (CRISPR)

CAT#: KN200641BN

NNMT - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: NNMT
• Locus ID: 4837
• Components:

  KN200641G1, NNMT gRNA vector 1 in pCas-Guide CRISPR vector

  KN200641G2, NNMT gRNA vector 2 in pCas-Guide CRISPR vector

  KN200641BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_006169
• UniProt ID: P40261
• Synonyms: nicotinamide N-methyltransferase
• Summary: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]