Mouse Taf1 activation kit by CRISPRa
CAT#: GA216093
Taf1 CRISPRa kit - CRISPR gene activation of mouse TATA-box binding protein associated factor 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Taf1 |
Locus ID | 270627 |
Kit Components | GA216093G1, Taf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216093G2, Taf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216093G3, Taf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001081008, NM_001290729 |
UniProt ID | Q80UV9 |
Synonyms | 250kDa; AU015687; B430306D02Rik; Ccg-1; Ccg1; KAT4; N-TAF1; Taf2a; TAFII250 |
Summary | Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:10438527). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
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KN517135 | Taf1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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