Mouse Rpl23a activation kit by CRISPRa

CAT#: GA215923

Rpl23a CRISPRa kit - CRISPR gene activation of mouse ribosomal protein L23A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Rpl23a
• Locus ID: 268449
• Kit Components:

  GA215923G1, Rpl23a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215923G2, Rpl23a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215923G3, Rpl23a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_207523
• UniProt ID: P62751
• Synonyms: BC029892; MDA20
• Summary: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity).[UniProtKB/Swiss-Prot Function]