Mouse Lingo1 activation kit by CRISPRa
CAT#: GA214621
Lingo1 CRISPRa kit - CRISPR gene activation of mouse leucine rich repeat and Ig domain containing 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Lingo1 |
Locus ID | 235402 |
Kit Components | GA214621G1, Lingo1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214621G2, Lingo1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214621G3, Lingo1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001311076, NM_181074, NM_001361115, NM_001361116, NM_001361117, NM_001361118, NM_001361119, NM_001361120 |
UniProt ID | Q9D1T0 |
Synonyms | 4930471K13Rik; AV148400; LERN1; LINGO-1; Lrrn6a; UNQ201 |
Summary | Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN509305 | Lingo1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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