Mouse Lsm10 activation kit by CRISPRa

CAT#: GA212451

Lsm10 CRISPRa kit - CRISPR gene activation of mouse U7 snRNP-specific Sm-like protein LSM10

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Lsm10
• Locus ID: 116748
• Kit Components:

  GA212451G1, Lsm10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212451G2, Lsm10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212451G3, Lsm10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163266, NM_138721
• UniProt ID: Q8QZX5
• Summary: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed (By similarity). Required for cell cycle progression from G1 to S phases (By similarity). Binds specifically to U7 snRNA (By similarity). Binds specifically to U7 snRNA (By similarity). Binds to the downstream cleavage product (DCP) of histone pre-mRNA.[UniProtKB/Swiss-Prot Function]