Mouse Rap2b activation kit by CRISPRa

CAT#: GA209672

Rap2b CRISPRa kit - CRISPR gene activation of mouse RAP2B, member of RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Rap2b
• Locus ID: 74012
• Kit Components:

  GA209672G1, Rap2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA209672G2, Rap2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA209672G3, Rap2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_028712
• UniProt ID: P61226
• Synonyms: 4021402C18Rik; AA408554
• Summary: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.[UniProtKB/Swiss-Prot Function]