Mouse Ttc19 activation kit by CRISPRa

CAT#: GA209343

Ttc19 CRISPRa kit - CRISPR gene activation of mouse tetratricopeptide repeat domain 19

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ttc19
• Locus ID: 72795
• Kit Components:

  GA209343G1, Ttc19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA209343G2, Ttc19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA209343G3, Ttc19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_028360, NM_029704
• UniProt ID: Q8CC21
• Synonyms: 2010204O13Rik; 2810460C24Rik; AI505442
• Summary: Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).[UniProtKB/Swiss-Prot Function]