Mouse Kynu activation kit by CRISPRa

CAT#: GA208618

Kynu CRISPRa kit - CRISPR gene activation of mouse kynureninase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Kynu
• Locus ID: 70789
• Kit Components:

  GA208618G1, Kynu gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208618G2, Kynu gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208618G3, Kynu gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289593, NM_001289594, NM_027552
• UniProt ID: Q9CXF0
• Synonyms: 4432411A05Rik
• Summary: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.[UniProtKB/Swiss-Prot Function]