Mouse Bag5 activation kit by CRISPRa

CAT#: GA208493

Bag5 CRISPRa kit - CRISPR gene activation of mouse BCL2-associated athanogene 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Bag5
• Locus ID: 70369
• Kit Components:

  GA208493G1, Bag5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208493G2, Bag5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208493G3, Bag5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001324480, NM_001324481, NM_001324482, NM_027404
• UniProt ID: Q8CI32
• Synonyms: 1600025G07Rik; 4930405J06Rik; Bag-5
• Summary: May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (By similarity).[UniProtKB/Swiss-Prot Function]