Mouse Mrm3 activation kit by CRISPRa

CAT#: GA207302

Mrm3 CRISPRa kit - CRISPR gene activation of mouse mitochondrial rRNA methyltransferase 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Mrm3
• Locus ID: 67390
• Kit Components:

  GA207302G1, Mrm3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207302G2, Mrm3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207302G3, Mrm3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_183263
• UniProt ID: Q5ND52
• Synonyms: 4833420N02Rik; AI255153; HC90; Rnmtl1
• Summary: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.[UniProtKB/Swiss-Prot Function]