Mouse Slc9a3r2 activation kit by CRISPRa

CAT#: GA206529

Slc9a3r2 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Slc9a3r2
• Locus ID: 65962
• Kit Components:

  GA206529G1, Slc9a3r2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206529G2, Slc9a3r2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206529G3, Slc9a3r2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_023055, NM_023449, NM_001357796
• UniProt ID: Q9JHL1
• Synonyms: 0610011L07Rik; 1200011K07Rik; 2010007A20Rik; E3karp; NHERF-2; Nherf2; Octs2; Sip-1
• Summary: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus (By similarity).[UniProtKB/Swiss-Prot Function]