Mouse Txndc17 activation kit by CRISPRa

CAT#: GA205511

Txndc17 CRISPRa kit - CRISPR gene activation of mouse thioredoxin domain containing 17

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Txndc17
• Locus ID: 52700
• Kit Components:

  GA205511G1, Txndc17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205511G2, Txndc17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205511G3, Txndc17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_026559
• UniProt ID: Q9CQM5
• Synonyms: 4831443O22Rik; D11Ertd672e; TRP14; Txnl5
• Summary: Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity).[UniProtKB/Swiss-Prot Function]