Mouse Hs6st1 activation kit by CRISPRa

CAT#: GA205365

Hs6st1 CRISPRa kit - CRISPR gene activation of mouse heparan sulfate 6-O-sulfotransferase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Hs6st1
• Locus ID: 50785
• Kit Components:

  GA205365G1, Hs6st1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205365G2, Hs6st1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205365G3, Hs6st1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015818
• UniProt ID: Q9QYK5
• Synonyms: 6Ost1
• Summary: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.[UniProtKB/Swiss-Prot Function]