Mouse Tnfrsf12a activation kit by CRISPRa

CAT#: GA205115

Tnfrsf12a CRISPRa kit - CRISPR gene activation of mouse tumor necrosis factor receptor superfamily, member 12a

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Tnfrsf12a
• Locus ID: 27279
• Kit Components:

  GA205115G1, Tnfrsf12a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205115G2, Tnfrsf12a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205115G3, Tnfrsf12a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161746, NM_013749
• UniProt ID: Q9CR75
• Synonyms: AI255180; C87282; Fn14; HPIP; TWEAK-R; TweakR
• Summary: Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[UniProtKB/Swiss-Prot Function]