Mouse Wt1 activation kit by CRISPRa
CAT#: GA204648
Wt1 CRISPRa kit - CRISPR gene activation of mouse Wilms tumor 1 homolog
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Wt1 |
Locus ID | 22431 |
Kit Components | GA204648G1, Wt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204648G2, Wt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204648G3, Wt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_144783 |
Synonyms | D630046I19Rik; Wt-1 |
Summary | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. [provided by RefSeq, Apr 2013] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN519472 | Wt1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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