Mouse Dusp8 activation kit by CRISPRa

CAT#: GA202990

Dusp8 CRISPRa kit - CRISPR gene activation of mouse dual specificity phosphatase 8

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Dusp8
• Locus ID: 18218
• Kit Components:

  GA202990G1, Dusp8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202990G2, Dusp8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202990G3, Dusp8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008748
• UniProt ID: O09112
• Synonyms: 5530400B01Rik; AI593498; Nttp1
• Summary: Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation (PubMed:7561881). Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues (Probable).[UniProtKB/Swiss-Prot Function]