Mouse Notch3 activation kit by CRISPRa
CAT#: GA202938
Notch3 CRISPRa kit - CRISPR gene activation of mouse notch 3
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Notch3 |
Locus ID | 18131 |
Kit Components | GA202938G1, Notch3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202938G2, Notch3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202938G3, Notch3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_008716 |
UniProt ID | Q61982 |
Synonyms | AW229011; hpbk; N3 |
Summary | Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May play a role during CNS development.[UniProtKB/Swiss-Prot Function] |
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Other Versions
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KN311126 | Notch3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN311126BN | Notch3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN311126LP | Notch3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN311126RB | Notch3 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN511126 | Notch3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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