Mouse Kcnh2 activation kit by CRISPRa

CAT#: GA202261

Kcnh2 CRISPRa kit - CRISPR gene activation of mouse potassium voltage-gated channel, subfamily H (eag-related), member 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Kcnh2
• Locus ID: 16511
• Kit Components:

  GA202261G1, Kcnh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202261G2, Kcnh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202261G3, Kcnh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001294162, NM_013569
• UniProt ID: O35219
• Synonyms: AI326795; ERG1; LQT; Lqt2; M-erg; Merg1; merg1a; merg1b
• Summary: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity).[UniProtKB/Swiss-Prot Function]